Proline LDH 21 FS (IFCC mod.)
| Catalogue Number | R1 Reagent Volume | R2 Reagent Volume |
| 14251 99 88 021 | 5 x 20 mL | 1 x 25 mL |
| 14251 99 88 920 | 4 x 32 mL | 4 x 8 mL |
Lactate dehydrogenase (LDH) is an enzyme, consisting of five different isoenzymes which catalyze the interconversion of L-lactate and pyruvate. LDH is present in the cytoplasm of all human tissues with higher concentrations in liver, heart and skeletal muscle and lower values in erythrocytes, pancreas, kidney and stomach. Increased LDH activities are found in a variety of pathological conditions such as myocardial infarction, cancer, diseases of liver, blood or muscle. However, because of the lack of organ specificity, determination of its isoenzymes or other enzymes such as alkaline phosphatase or ALAT/ASAT is necessary for differential diagnosis.
Proline LDH 21 FS (IFCC mod.) comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.
Proline LDH 21 FS (IFCC mod.) reagent is suitable for various third party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. Please contact our technical support at marketing@proline.co.id for further compatibility information on other types of analyzers.
- Optimized UV-test according to IFCC (International Federation of Clinical Chemistry and Laboratory Medicine).
- No interfering substances: Ascorbic acid 60 mg/dL, Bilirubin (conjugated) 60 mg/dL, Lipemia (triglycerides) 2000 mg/dL, Sulfapyridine 30 mg/dL, Sulfasalazine 30 mg/dL.
- Measurement linearity reaches 1500 U/L, with a lower limit of detection of 15 U/L.
| Reference Range: | ||||
| Woman | Man | |||
| U/L | µkat/L | U/L | µkat/L | |
| Adult | < 247 | < 4.12 | < 248 | < 4.14 |
| Children | ||||
| 1 – 30 Day(s) | 145 – 765 | 2.42 – 12.8 | 125 – 735 | 2.09 – 12.3 |
| 31 – 365 Days | 190 – 420 | 3.17 – 7.01 | 170 – 450 | 2.84 – 7.52 |
| 1 – 3 Year(s) | 165 – 395 | 2.76 – 6.60 | 155 – 345 | 2.59 – 5.76 |
| 4 – 6 Years | 135 – 345 | 2.25 – 5.76 | 155 – 345 | 2.59 – 5.76 |
| 7 – 9 Years | 140 – 280 | 2.34 – 4.68 | 145 – 300 | 2.42 – 5.01 |
| 10 – 12 Years | 120 – 260 | 2.00 – 4.34 | 120 – 325 | 2.00 – 5.43 |
| 13 – 15 Years | 100 – 275 | 1.67 – 4.59 | 120 – 290 | 2.00 – 4.84 |
| 16 – 18 Years | 105 – 230 | 1.75 – 3.84 | 105 – 235 | 1.75 – 3.92 |
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary.
- Lactate Dehydrogenase Reagent
- Doos
- Kit insert
- Reagents bottle
- Thomas L. Clinical laboratory diagnostics. 1st ed. Frankfurt: TH-Books Verlagsgesellschaft; 1998. p. 89-94.
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- Bakker AJ, Mücke M. Gammopathy interference in clinical chemistry assays: Mechanisms, detection and prevention. Clin Chem Lab med 2007; 45(9): 1240-1243.
- Guder WG, Zawta B et al. The Quality of Diagnostic Samples. 1st ed. Darmstadt: GIT Verlag; 2001; p. 36-7.
- Young DS. Effects of Drugs on Clinical Laboratory Tests. 5th ed. Volume 1 and 2. Washington, DC: The American Association for Clinical Chemistry Press 2000.
- Young DS. Effects on Clinical Laboratory Tests - Drugs Disease, Herbs & Natural Products, https://clinfx.wiley.com/aaccweb/aacc/, accessed in March 2021. Published by AACC Press and John Wiley and Sons, Inc.
- Schumann G, Bonora R, Ceriotti F, Férard G et al. IFCC primary reference procedure for the measurement of catalytic activity concentrations of enzymes at 37°C. Part 3: Reference procedure for the measurement of catalytic concentration of lactate dehydrogenase. Clin Chem Lab Med 2002;40:643-48.
- Soldin JS, Hicks JM. Pedia
- Liver disease
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- Telp : +62 21 8984 2722
- WhatsApp : +62 815 1359 2626
- Email : marketing@proline.co.id
Contact our Technical support team for further assistance with product specifications, services and other technical documents.
- Telp : +62-21-8984-2722
- WhatsApp : +62-817-9324-884
- Email : technical.support@prodis.co.id