Cystatin C FS

Product Number: 1 7158


Cystatin C is a non-glycylated basic protein with a low molecular weight of 13 kDa. Cystatin C can act as a cysteine ​​protease inhibitor. Cystatins are produced at a constant rate by all nucleated cells and filtered by the glomerular membrane before being completely absorbed and degraded in the renal tubules. Cystatin C suggests a better marker for detecting decreased glomerular filtration rate (GFR) compared to creatinine, especially for detecting impaired renal function. Cystatin C levels in the blood are different from creatinine, where cystatin C is not determined by sex, muscle mass and age. Determining cystatin C is particularly useful in children, the elderly, diabetics, people with liver cirrhosis, adults receiving kidney transplants, people with cancer and suspected preeclampsia.


Ready to use reagent.

Proline Cystatin C FS comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.

Open system reagent, compatible with a wide range of instruments.

Proline Cystatin C FS reagent is suitable for various third party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. Please contact our technical support at for further compatibility information on other types of analyzers.


  • Particle enhanced immunoturbidimetric test.
  • No interference: bilirubin 60 mg/dL, hemoglobin 1000mg/dL, lipemia to triglycerides 1000mg/dL and RF 600 IU/mL
  • Measurement linearity reached 8 mg/dL , with a lower limit of detection of 0.08 mg/dL


Kit Lines

No. Catalog R1 R2 Kit Size
1 7158 99 10 921  4 X 20 mL 4 X 8 mL Proline® R-910
1 7158 99 10 966 2 X 13 mL 2 X 5 mL Other Automated Instrument

Reference Range

Cystatin C is a marker of decreased glomerular filtration rate (GFR), especially to detect moderate renal function impairment. Cystatin C levels were independent of sex, muscle mass, and age.

19 - 49 years 0.53 – 0.92 mg/L
≥ 50 years 0.58 – 1.02 mg/L
4-5 days 1.22 - 1.68 mg/L
< 1 month 1.37 - 1.89 mg/L
1 - 12 month(s) 0.73 - 1.17 mg/L
> 12 months 0.60 - 0.84 mg/L


  • Kidney disease

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