Proline CRP FS
| Catalogue Number | R1 Reagent Volume | R2 Reagent Volume |
| 1 7002 99 88 920 | 4 x 36 mL | 4 x 8 mL |
| 1 7002 99 88 021 | 5 x 25 mL | 1 x 25 mL |
A diagnostic reagent for the quantitative examination of C-reactive protein (CRP) in serum or plasma in vitro by a photometric system.
CRP is a pentameric protein synthesized by the liver, whose level rises in response to inflammation. CRP is an acute-phase reactant protein that is primarily induced by the IL-6 action on the gene responsible for the transcription of CRP during the acute phase of an inflammatory/infectious process.
C-reactive protein (CRP) plays an important role in the inflamantory process, activating celluler defense pathways, protecting against bacterial infections, protecting the body by binding to phatogens such as Streptococcus pneumoniae and Salmonella enterica and as a means of initial cleaning of bacteria to other organs such as the liver and spleen.
C-reactive protein (CRP) levels can be affected by a variety of conditions and medications. High CRP levels, especially those above 50 mg/dL, are strongly associated with bacterial infections such as hepatitis C, dengue fever, and malaria. The normal range for CRP in the body is between 1 mg/dL and 10 mg/dL. Chronic conditions such as inflammatory arthritis or systemic lupus erythematosus (SLE) can cause persistent elevations in CRP, making it difficult to use as a predictive marker for cardiovascular disease. In addition, factors such as obesity, insomnia, depression, smoking, and diabetes can also contribute to mild elevations in CRP. Medications such as NSAIDs, statins, and magnesium supplements can affect CRP levels.
Immunoturbidimetric test.
- Ready-to-use liquid reagent (open-system) without reconstitution.
- Excellent linearity and stability performance.
- Available in MPK (Multi-Purpose Kit) and dedicated kit.
| Sample type | Serum, heparin plasma or EDTA plasma |
| Measurement range | 2 mg/L - 250 mg/L |
| Analysis wavelength | 340 nm, Hg 334 nm |
| Analysis mode | End point |
| Reagent volume used (analyzer manual) | 15 µL - 250 µL |
| Sample volume used (analyzer manual) | 15 µL |
| Storage temperature | 2 – 8 °C |
| Open vial stability | 18 months |
| Expiration date | 24 months |
| Control for CRP Reagent | Calibrator for CRP Reagent |
| TruLab CRP Level 1 | TruCal CRP 5 Level |
| TruLab CRP Level 2 | |
| TruLab Protein Level 1 | |
| TruLab Protein Level 2 |
| Reference Range: | ||
| Adults | < 5 mg/dL | |
| Newborn up to 3 weeks | < 4.1 mg/L | |
| Infants and children | < 2.8 mg/L | |
- CRP Reagent C-reactive protein (CRP)
- Doos
- Kit insert
- Reagents bottle
- PROLINE CRP FS Kit Insert (17002 01 – Mar 2024/00)
- Nehring SM, Goyal A, Patel BC. C Reactive Protein. [Updated 2023 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441843/
- Sproston NR, Ashworth JJ. Role of C-Reactive Protein at Sites of Inflammation and Infection. Front Immunol. 2018 Apr 13;9:754. doi: 10.3389/fimmu.2018.00754. PMID: 29706967; PMCID: PMC5908901.
- Brochure : INA
- Inflammation
- Atherosclerosis
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