PROLINE ALAT (GPT) FS (IFCC mod.)
Diagnostic reagent for the quantitative determination of ALAT (GPT) in serum or heparin plasma in vitro using a photometric system.
Alanine aminotransferase (ALAT/ALT), previously known as Glutamic Pyruvic Transaminase (GPT), is the most important enzyme in the aminotransferase or transaminase group, which catalyzes the conversion of α-keto acids to amino acids through the transfer of an amino group. As a liver-specific enzyme, ALAT will only increase significantly in hepatobiliary diseases. The AST/ALT ratio is crucial for differential diagnosis in liver diseases and is used to distinguish damage to the liver, heart, or skeletal muscles.
In liver cirrhosis, liver tissue is damaged and replaced by scar tissue (fibrosis), leading to portal hypertension. This high pressure forces blood to flow through alternative vessels, such as esophageal varices, which can rupture and cause bleeding. Additionally, alanine aminotransferase (ALAT) enzymes are released into the blood, indicating liver cell damage.
The optimized UV test according to the IFCC (International Federation of Clinical Chemistry and Laboratory Medicine).
- Ready-to-use liquid reagent (open-system) without reconstitution
- Excellent linearity and stability performance
- Available in MPK (Multi-Purpose Kit) and dedicated kit
- Compatible with >65 brands of manual and automated clinical chemistry analyzers
| Sample type | Human heparin serum or plasma |
| Measurement range | 3 U/L - 600 U/L |
| Analysis wavelength | 340 nm |
| Analysis mode | Kinetic |
| Reagent volume used (analyzer manual) | R1: 1000 µL ; R2: 250 µL |
| Sample volume used (analyzer manual) | 100 µL |
| Storage temperature | 2 – 8 °C |
| Open vial stability | 12 months |
| Expiration date | 15 months |
| Reference Range: | ||
| U/L | μkat/L | |
| With P-5-P | ||
| Woman | <34 | <0.57 |
| Man | <45 | <0.75 |
| Children | < | |
| 1 - 3 days | <25 | <0.42 |
| 2 - 12 months | <35 | <0.58 |
| 1 - 3 years | <30 | <0.50 |
| 4 - 6 years | <25 | <0.42 |
| 7 - 9 years | <25 | <0.42 |
| 10 - 18 years | <30 | <0.50 |
| Without P-5-P | ||
| Woman | <31 | <0.52 |
| Man | <41 | <0.68 |
- Alanine Aminotransferase (ALAT/GPT) Reagent
- Doos
- Kit insert
- Reagents bottle
- Kit Insert PROLINE ALAT (GPT) FS (IFCC mod.) ()12701 01 – Sep 2024/01.
- Pradnyawati, N. (2018). ANALISIS KADAR ALBUMIN SERUM TERHADAP ASPARTATE TRANSAMINASE (AST), ALANIN TRANSAMINASE (ALT) DAN RASIO DE RITIS PADA PASIEN HEPATITIS B DI RSUP SANGLAH, DENPASAR. E-Jurnal Medika Udayana, 7(6).
Retrieved from https://ojs.unud.ac.id/index.php/eum/article/view/41450 - Sutrisna, M. (2020). HUBUNGAN TANDA-TANDA HIPERTENSI PORTAL DENGAN KEJADIAN PERDARAHAN VARISES ESOPHAGUS PADA PASIEN SIROSIS HEPATIS. Journal of Nursing and Public Health, 8(1), 66-72. https://doi.org/10.37676/jnph.v8i1.1015.
- Brochure : INA
- Liver disease
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