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ALAT (GPT) FS (IFCC mod.)

Product number: 1 2701

Description

Alanine Aminotransferase (ALAT/ALT), formerly called Glutamic Pyruvic Transaminase (GPT) and Aspartate Aminotransferase (ASAT/AST), formerly called Glutamic Oxalacetic Transaminase (GOT) are the most important representatives of a group of enzymes, the aminotransferases or transaminases, which catalyze the conversion of α-keto acids into amino acids by transfer of amino groups. As a liver-specific enzyme, ALAT is only significantly elevated in hepatobiliary diseases. Increased ASAT levels, however, can occur in connection with damages of heart or skeletal muscle as well as of liver parenchyma. Parallel measurement of ALAT and ASAT is, therefore, applied to distinguish liver from heart or skeletal muscle damages. The ASAT/ALAT ratio is used for differential diagnosis in liver diseases. While ratios < 1 indicate mild liver damage, ratios > 1 are associated with severe, often chronic liver diseases.

Increased in

  • Hepatitis Virus
  • Toxic hepatitis
  • Infectious Mononucleosis
  • Cirrhosis
  • Polymyositis
  • Acute pancreatitis

Decreased in

  • End stage liver disease
  • Renal hemodialysis and/or renal insufficiency

Feature

Ready to use reagent.

Proline ALAT (GPT) FS (IFCC mod.) comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.

Open system reagent, compatible with a wide range of instruments.

Proline ALAT (GPT) FS (IFCC mod.) reagent is suitable for various third party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki and Beckman Coulter. Please contact our technical support at marketing@proline.co.id for further compatibility information on other types of analyzers.

Specification

  • Optimal UV Test according to IFCC (International Federation of Clinical Chemistry and Laboratory Medicine)
  • No interference: ascorbic acid 30mg/dL, bilirubin 40mg/dL, and hemoglobin 400mg/dL
  • Measurement linearity is up to 600 U/L, with a lower limit of detection of 4 U/L

Calibrator

Control

Kit Lines

No. Catalogue R1 R2 Kit Size
1 2701 99 10 022  5 X 20 mL 1 X 25 mL Multi Purpose Kit
1 2701 99 10 025 3 X 80 mL 1 X 60 mL Multi Purpose Kit
1 2701 99 10 029 3 X 200 mL 1 X 150 mL Multi Purpose Kit
1 2701 99 10 181 4 X 36 mL 4 X 9 mL TMS50i
1 2701 99 10 191 4 X 36 mL 4 X 9 mL TMS24i
1 2701 99 10 591 4 X 60 mL 4 X 15 mL Mindray
1 2701 99 10 914 6 X 60 mL 6 X 15 mL Hitachi 917
1 2701 99 10 920 4 X 34 mL 4 X 10 mL Proline® R-910
1 2701 99 10 921 4 X 21 mL 4 X 6 mL Proline® R-910
1 2701 99 10 951 6 X 36 mL 6 X 9 mL Advia
1 2701 99 10 965 6 X 25 mL 6 X 6 mL Other Automated Instrument

Reference Range

With pyridoxal-5-phosphate activation

Men <34 U/L <0.57 μkat/L
Women <45 U/L <0.75 μkat/L
Children    
  1 - 30 days <25 U/L <0.42 μkat/L
  2 - 12 months <35 U/L <0.58 μkat/L
  1 - 3 year <30 U/L <0.50 μkat/L
  4 - 6 year <25 U/L <0.42 μkat/L
  7 - 9 year <25 U/L <0.42 μkat/L
  10 - 18 year <30 U/L <0.50 μkat/L

 

Without pyridoxal-5-phosphate activation

Men <34 U/L <0.57 μkat/L
Women <45 U/L <0.75 μkat/L

 

Each laboratory should check whether the reference range can be calculated for its patient population and determine its own reference range if necessary.

For diagnostic purposes, outcomes should always be assessed against the patient's medical history, clinical examination, and other findings.

Related Product

Category

  • Liver Disease

Order information

Reach out to our team for more product and orders information.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 815 1359 2626
  • Email. marketing@proline.co.id

Technical Support

Contact our Technical Assistance team for further assistance with product specifications, services and other technical documents.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 817 9324 884
  • Email. technical.support@prodis.co.id
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