Calcium P FS
Calcium plays an essential role in many cell functions: intracellular in muscle contraction and glycogen metabolism, extracellular in bone mineralization, in blood coagulation and in transmission of nerve impulses. Calcium in plasma exists in three forms: free, bound to proteins or bound to anions such as phosphate, citrate and bicarbonate in a complex reaction. Decreased total calcium levels can be associated with diseases of the bone apparatus (especially osteoporosis), kidney diseases (especially under dialysis), defective intestinal absorption and hypoparathyroidism. Increased total calcium can be measured in hyperparathyroidism, malignant diseases with metastases and sarcoidosis. Calcium measurements also help in monitoring of calcium supplementation mainly in the prevention of osteoporosis.
- Metastatic carcinoma
- Thiazide therapy
- Decreased muscle mass (eg muscular dystrophy, myasthenia gravis)
Proline Calcium P FS comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.
Proline Calcium P FS reagent is suitable for various third party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. Please contact our technical support at firstname.lastname@example.org for further compatibility information on other types of analyzers.
- Photometric endpoint determination with Phosphonazo III
- No interference: ascorbic acid 30 mg/dL, bilirubin 60 mg/dL, hemoglobin 1000mg/dL, lipemia to triglycerides 2000mg/dL, and magnesium 20 mg/dL
- Measurement linearity reached 25 mg/dL (6.24 mmol/L), with a lower limit of detection 0.2 mg/dL
|Adults||8.6 – 10.3 mg/dL||2.15 – 2.57 mmol/L|
|New born or premie||6.2-11.0 mg/dL||1.55-2.75 mmol/L|
|Children < 10 days||7.6-10.4 mg/dL||1.90-2.60 mmol/L|
|Children 11 days - 2 years||9.0-11.0 mg/dL||2.25-2.75 mmol/L|
|Children 3-12 years||8.8-10.8 mg/dL||2.20-2.70 mmol/L|
|Children 13-18 years||8.4-10.2 mg/dL||2.10-2.55 mmol/L|
|Women||< 250 mg/24h||6.24 mmoL/24h|
|Men||< 300 mg/24h||7.49 mmoL/24h|
Each laboratory should check if the reference ranges are transferable to its own patient population and determine its own reference ranges if necessary.
- Thomas L. Clinical Laboratory Diagnostics. 1st ed. Frankfurt: TH-Books Verlagsgesellschaft; 1998. p. 231-241.
- Endres DB, Rude RK. Mineral and bone metabolism. In: Burtis CA, Ashwood ER, editors. Tietz Textbook of Clinical Chemistry. 3rd ed. Philadelphia: W.B Saunders Company; 1999. p. 1395-1406.
- Guder WG, Zawta B et al. The Quality of Diagnostic Samples. 1st ed. Darmstadt:
- GIT Verlag; 2001. p. 20-1 and p. 50-1.
Young DS. Effects of Drugs on Clinical Laboratory Tests. 5th ed. Volume 1 and 2. Washington, DC: The American Association for Clinical Chemistry Press 2000.
- Bakker AJ, Mücke M. Gammopathy interference in clinical chemistry assays: mechanisms, detection and prevention. ClinChemLabMed 2007;45(9):1240- 1243.
- Bone Metabolism
- Liver Disease
Reach out to our team for more product and orders information.
- Phone. +6221 8984 2722
- WhatsApp. +62 815 1359 2626
- Email. email@example.com
Contact our Technical Assistance team for further assistance with product specifications, services and other technical documents.
- Phone. +6221 8984 2722
- WhatsApp. +62 817 9324 884
- Email. firstname.lastname@example.org