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Gamma-GT FS (Szasz mod./IFCC stand.)

PROLINE Gamma-GT FS (Szasz mod./IFCC stand.)

Kit Lines

Catalogue Number R1 Reagent Volume R2 Reagent Volume
12801 99 10 920 4 x 38 mL 4 x 11 mL
12801 99 10 921 4 x 23 mL 4 x 7 mL
12801 99 10 191 4 x 36 mL 4 x 9 mL
12801 99 10 181 4 x 36 mL 4 x 9 mL
12801 99 10 022 5 x 20 mL 1 x 25 mL
12801 99 10 965 6 x 25 mL 6 x 6 mL
12801 99 10 914 6 x 60 mL 6 x 15 mL
12801 99 10 951 6 x 36 mL 6 x 9 mL
12801 99 10 591 4 x 60 mL 4 x 15 mL
12801 99 10 027 2 x 100 mL 2 x 25 mL

Product Description

In vitro diagnostic reagent for quantitative examination of gamma-glutamyltransferase (Gamma-GT/GGT) in serum or plasma using the photometric test method.

Gamma-Glutamyl Transferase (GGT) is an enzyme found primarily in the liver, but also in the kidneys, pancreas, and intestines. This enzyme plays a role in glutathione metabolism and amino acid transport across cell membranes. Blood GGT levels are often used as an indicator of liver function, particularly in detecting damage to the bile ducts and liver caused by alcohol consumption or hepatotoxic drugs.

The Role of Gamma-Glutamyl Transferase in the Human Body

The primary function of GGT is the transfer of gamma-glutamyl groups from glutathione to recipient molecules, which is essential for detoxification and cellular metabolism. GGT activity allows cells to uptake essential amino acids, aids in the regeneration of intracellular glutathione, and maintains redox balance in the body. Therefore, GGT is also thought to play a role in protecting cells against oxidative stress.

Gamma-Glutamyl Transferase and Liver Function

High GGT levels in the blood are generally associated with various liver conditions, such as hepatitis, cirrhosis, and alcoholic liver disease. Furthermore, elevated GGT can also be an indicator of cholestasis (impaired bile flow), liver cancer, and even heart disease and diabetes mellitus. GGT testing is often used in conjunction with other liver function tests to confirm the diagnosis and determine the specific cause of liver disorders.

Measurement Method

Kinetic photometric test according to Szasz/Persijn. This test has also been standardized according to the IFCC (International Federation of Clinical Chemistry).

Product Advantages

  • Ready-to-use liquid reagent (open-system) without reconstitution
  • Excellent linearity and stability performance
  • Available in MPK (Multi-Purpose Kit) and dedicated kit
  • Compatible with >65 brands of manual and automated clinical chemistry analyzers

Specifications

Sample type Human serum or heparin plasma
Measurement range 1.73 U/L - 1470 U/L
Analysis wavelength 405 nm (400 – 420 nm)
Analysis mode Kinetics
Reagent volume used (analyzer manual) R1: 1000 µL ; R2: 250 µL
Sample volume used (analyzer manual) 100 µL
Storage temperature 2 – 8 °C
Open vial stability 12 months
Expiration date 15 months

Control and Calibrator

Control for Gamma-GT Reagent Calibrator for Gamma-GT Reagent
TruLab N TruCal U
TruLab P

Reference Range

Reference Range:
Woman Man
U/L µkat/L U/L µkat/L
Adult < 32 < 0.53 < 49 < 0.82
Woman Man
U/L µkat/L U/L µkat/L
Children
1 - 7 days 18 - 148 0.30 – 2.47 25 – 168 0.42 – 2.80
8 - 30 days 16 - 140 0.27 – 2.33 23 – 174 0.38 – 2.90
1 - 3 months 16 - 140 0.27 – 2.33 16 – 147 0.27 – 2.45
4 - 6 months 13 - 123 0.22 – 2.05 5 – 93 0.08 – 1.55
7 - 12 months 8 - 59 0.13 – 0.98 8 – 38 0.13 – 0.63
1 - 3 years 2 - 15 0.03 – 0.25 2 – 15 0.03 – 0.25
4 - 6 years 5 - 17 0.08 – 0.28 5 – 17 0.08 – 0.28
7 - 9 years 9 - 20 0.15 – 0.33 9 – 20 0.15 – 0.33
10 - 11 years 12 - 23 0.20 – 0.38 12 – 25 0.20 – 0.42
12 - 13 years 10 - 20 0.17 – 0.33 12 – 39 0.20 – 0.65
14 - 19 years 6 - 23 0.10 – 0.38 6 – 30 0.10 – 0.50
Adult < 40 < 0.65 < 60 < 1.00

Product Content

Name

  • Gamma-Glutamyl Transferase Reagent

Kit Content

  • Doos
  • Kit insert
  • Reagents bottle

Journal

  • Kit Insert PROLINE Gamma-GT FS (Szasz mod./IFCC stand.) (12801 01 – Sep 2024/03)
  • Whitfield, J. B. (2001). Gamma glutamyl transferase. Critical Reviews in Clinical Laboratory Sciences, 38(4), 263–355. https://doi.org/10.1080/20014091084227
  • Lee, D. H., & Jacobs, D. R. Jr. (2005). Association between serum gamma-glutamyltransferase and C-reactive protein. Atherosclerosis, 178(2), 327–330. https://doi.org/10.1016/j.atherosclerosis.2004.08.041
  • Emdin, M., Passino, C., Michelassi, C., et al. (2001). Prognostic value of serum gamma-glutamyl transferase activity after myocardial infarction. European Heart Journal, 22(19), 1802–1807. https://doi.org/10.1053/euhj.2001.2663

Download

  • Brochure : INA 

Category

  • Liver disease
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Order information

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  • WhatsApp :  +62 815 1359 2626
  • Email : marketing@proline.co.id

Technical Support

Contact our Technical support team for further assistance with product specifications, services and other technical documents.

  • Telp : +62-21-8984-2722
  • WhatsApp :  +62-817-9324-884
  • Email : technical.support@prodis.co.id
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