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Iron FS

Product Number: 1 1911

Description

Iron exists in the body as a component of hemoglobin and myoglobin and is bound to transferrin for transport in plasma and stored in ferritin. Increased iron concentration occurs in hemochromatosis and liver damage. Malabsorption is a digestive disease that can cause a decrease in iron levels, and thus can cause anemia. Blood loss after gastrointestinal lesions or heavy menstrual bleeding can cause anemia as well.

Increased in

  • Hemochromatosis
  • Hemosiderosis from excessive iron intake
  • Decreased red blood cell formation (eg thalassemia, pyridoxine deficiency anemia, aplastic anemia)
  • Hemolytic anemia
  • Acute liver damage
  • Iron poisoning
  • Lead toxicity

Decreased in

  • Iron-deficiency anemia (hypochromic, microcytic)
  • Late pregnancy (28 weeks to birth)
  • Chronic infection
  • Period
  • Nephrosis
  • Kwashiorkor syndrome (acute malnutrition)

Features

Ready to use reagent.

Proline Iron FS Ferene comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.

Open system reagent, compatible with a wide range of instruments.

Proline Iron FS Ferene reagent is suitable for various third-party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. Please contact our technical support at marketing@proline.co.id for further compatibility information on other types of analyzers.

Specification

  • Photometric test using Ferene
  • No interference: hemoglobin 100 mg/dL, bilirubin 60 mg/dL, lipemia to triglycerides 2000mg/dL, copper 200 g/dL and Zinc 400 g/dL
  • Measurement linearity reaches 1000 g/dL, with a lower limit of detection of 5 g/dL

Calibrator

Control

Kit Lines

No. Catalog R1 R2 Kit Size
1 1911 99 10 021 4 x 20 mL 1 x 20 mL Multi Purpose Kit
1 1911 99 10 026  5 x 80 mL  1 x 100 mL   Multi Purpose Kit
1 1911 99 10 023  1 x 800 mL  1 x 200 mL   Multi Purpose Kit
1 1911 99 10 704  8 x 50 mL  8 x 12,5 mL   Hitachi 704/717/902/911/912
1 1911 99 10 917  8 x 60 mL  8 x 15 mL   Hitachi 917
1 1911 99 10 930  4 x 20 mL  2 X 10 mL   Hitachi 704/717/902/911/912/917
1 1911 99 10 921  4 x 21 mL  4 X 6 mL   Proline® R-910

Reference Range

Magnesium (Mg2+) fulfills various functions in the human body. Complications associated with decreased Mg levels are neuromuscular irritability and cardiac symptoms. An increase in the magnesium value can be observed e.g. in dehydration or renal impairment.

Women
25 years 37 – 165 µg/dL 6.6 – 29.5 µmol/L
40 years 23 – 134 µg/dL 4.1 – 24.0 µmol/L
60 years 39 – 149 µg/dL 7.0 – 26.7 µmol/L
 
Women (pregnant)
12 weeks pregnancy 42 – 177 µg/dL 7.6 – 31.6 µmol/L
Pergnancy 25 – 137 µg/dL 4.5 – 24.5 µmol/L
6 weeks postpartum 16 – 150 µg/dL 2.9 – 26.9 µmol/L
 
Men
25 years 40 – 155 µg/dL 7.2 – 27.7 µmol/L
40 years 35 – 168 µg/dL 6.3 – 30.1 µmol/L
60 years 40 – 120 µg/dL 7.2 – 21.5 µmol/L
 
Children
2 weeks 63 – 201 µg/dL 11 – 36 µmol/L
6 months 28 – 135 µg/dL 5 – 24 µmol/L
12 months 35 – 155 µg/dL 6 – 28 µmol/L
2 – 12 years 22 – 135 µg/dL 4 – 24 µmol/L

Each laboratory should check if the reference ranges are transferable to its own patient population and determine its own reference ranges if necessary

References

  1. Wick M. Iron metabolism and its disorders. In: Thomas L, editor. Clinical laboratory diagnostics. 1st ed. Frankfurt: THBooks Verlagsgesellschaft; 1998. p. 268-73.
  2. Fairbanks VF, Klee GG. Biochemical aspects of hematology. In: Burtis CA, Ashwood ER, editors. Tietz Textbook of Clinical Chemistry. 3rd ed. Philadelphia: W.B Saunders Company; 1999. p. 1642–1710.
  3. Guder WG, Zawta B et al. The Quality of Diagnostic Samples. 1st ed. Darmstadt: GIT Verlag; 2001; p. 34-5.
  4. Thomas L. Clinical Laboratory Diagnostics. 1st ed. Frankfurt: TH-Books Verlagsgesellschaft; 1998. p. 273-5.
  5. Higgins T. Novel chromogen for serum iron determinations. Clin Chem 1981; 27: 1619.
  6. Artiss JD, Vinogradov S, Zak B. Spectrophotometric study of several sensitive reagents for serum iron. Clin Biochem 1981; 14: 311-15.
  7. Young DS. Effects of Drugs on Clinical Laboratory Tests. 5th ed. Volume 1 and 2. Washington, DC: The American Association for Clinical Chemistry Press 2000.
  8. Bakker AJ, Mücke M. Gammopathy interference in clinical chemistry assays: mechanisms, detection and prevention. ClinChemLabMed 2007;45(9):1240–1243

Category

  • Nutrition
  • Kidney Disease

Order information

Reach out to our team for more product and orders information.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 815 1359 2626
  • Email. marketing@proline.co.id

Technical Support

Contact our Technical Assistance team for further assistance with product specifications, services and other technical documents.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 817 9324 884
  • Email. technical.support@prodis.co.id
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