Ferritin FS

Product Number: 1 7059


Ferritin is an iron storage protein consisting of 24 subunits that form a hollow sphere up to 4000 iron atoms can be closed. Ferritin containing iron is the main source of iron reserves for every cell and all organisms available for the synthesis of hemoglobin. Variations in serum ferritin are generally closely related to changes in tissue ferritin. Measurement of serum ferritin concentration provides a quantitative determination of mobilizable iron stores. Thus, decreased ferritin levels indicate iron tissue depletion and are very useful in early detection of the most common deficiency anemia for iron disorders in the industrialized world. Elevated serum ferritin concentrations can be suggestive of iron overload in conjunction with an iron storage disorder such as inherited disease or hemochromatosis. It can also be used to clinically evaluate conditions not associated with iron storage including chronic liver disease, infection, inflammation and other malignancies.

Increased in

  • Liver parenchymal damage
  • Malignant tumor

Decreased in

  • Iron storage anemia
  • Chronic blood loss
  • Malabsorption


Ready to use reagent.

Proline Ferritin FS comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.

Open system reagent, compatible with a wide range of instruments.

Proline Ferritin FS reagent is suitable for various third-party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. Please contact our technical support at for further compatibility information on other types of analyzers.


  • Immunoturbidimetric test (Particle enhanced)
  • No effect of prozone was seen up to a concentration of 30000 mg/L ferritin.
  • No interference: ascorbic acid 30 mg/dL, bilirubin 60 mg/dL, hemoglobin 1000 mg/dL, lipemia to triglycerides 1400 mg/dL
  • Measurement linearity reaches 1000 g/L with a lower limit of detection of 5 g/L



Kit Lines

No. Catalog R1 R2 Kit Size
1 7059 99 10 964 6 X 8 mL 6 X 8 mL Other Automated Instrument
1 7059 99 10 309 3 X 20 mL 3 X 10 mL Multi Purpose Kit
1 7059 99 10 930 3 X 20 mL 3 X 10 mL Hitachi 704/717/902/911/912/917
1 7059 99 10 935 1 X 20 mL 1 X 10 mL Hitachi 704/717/902/911/912/917

Reference Range

Ferritin is an iron storage protein; decreased levels indicate iron deficiency anemia, increased levels occur eg. in hemochromatosis.

 Men 30 – 400 µg/L
Women < 50 years 15 – 150 µg/L
Women > 50 years The approximate reference range for men
 4 months - 16 years 15 – 150 µg/L

Each laboratory should check whether the reference range can be calculated for its patient population and determine its own reference range if necessary.


  1. Wick  M,  Pingerra  W,  Lehmann  P,  Iron  metabolism:  diagnosis and  therapy  of  anemias,  5th  ed, Vienna,  New  York:  Springer Verlag, 2003; p. 151.
  2. Worwood  M.  The  laboratory  assessment  of  iron  status  –  an update. Clin Chim Acta 1997;259:3-23. 
  3. Kaltwasser  JP,  Werner  E.  Diagnosis  and  clinical  evaluation  of iron overload. Baillieres Clin Haematol 1989;2;363-89.
  4. Baynes RD,  Cook  JD.  Current  issues  in  iron  deficiency.  CurrOpin Hematol 1996;3:145-9.
  5. Guder WG,  Zawta  B  et  al.  The  Quality  of  Diagnostic  Samples. 1st ed. Darmstadt: GIT Verlag; 2001; p. 28-9.
  6.  Lee MH,  Means  RT  Jr.  Extremely  elevated  serum  ferritin  levels in a university hospital: associated diseases and clinical significance. Am J Med 1996;98:566-71.
  7. Young DS.  Effects  of  Drugs  on  Clinical  Laboratory  Tests.  5th e d . Volume 1 and 2. Washington DC: The American Association for Clinical Chemistry Press 2000.
  8. Bakker AJ, Mücke M. Gammopathy interference in clinical chemistry assays: mechanisms, detection and prevention. ClinChemLabMed 2007;45(9):1240-1243.


  • Iron Metabolism

Order information

Reach out to our team for more product and orders information.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 815 1359 2626
  • Email.

Technical Support

Contact our Technical Assistance team for further assistance with product specifications, services and other technical documents.

  • Phone. +6221 8984 2722
  • WhatsApp. +62 817 9324 884
  • Email.